Enhanced Ca(2+)-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease

Ca(2+) overload-induced mitochondrial dysfunction is considered as a major contributing factor in the pathogenesis of alcohol-associated liver disease (ALD). However, the initiating factors that drive mitochondrial Ca(2+) accumulation in ALD remain elusive. Here, we demonstrate that an aberrant incr...

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Detalles Bibliográficos
Autores principales: Thoudam, Themis, Chanda, Dipanjan, Lee, Jung Yi, Jung, Min-Kyo, Sinam, Ibotombi Singh, Kim, Byung-Gyu, Park, Bo-Yoon, Kwon, Woong Hee, Kim, Hyo-Jeong, Kim, Myeongjin, Lim, Chae Won, Lee, Hoyul, Huh, Yang Hoon, Miller, Caroline A., Saxena, Romil, Skill, Nicholas J., Huda, Nazmul, Kusumanchi, Praveen, Ma, Jing, Yang, Zhihong, Kim, Min-Ji, Mun, Ji Young, Harris, Robert A., Jeon, Jae-Han, Liangpunsakul, Suthat, Lee, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042999/
https://www.ncbi.nlm.nih.gov/pubmed/36973273
http://dx.doi.org/10.1038/s41467-023-37214-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042999/
https://www.ncbi.nlm.nih.gov/pubmed/36973273
http://dx.doi.org/10.1038/s41467-023-37214-4

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