Effect of sclerostin inactivation in a mouse model of severe dominant osteogenesis imperfecta

Osteogenesis imperfecta (OI) is a rare bone disease that is associated with fractures and low bone mass. Sclerostin inhibition is being evaluated as a potential approach to increase bone mass in OI. We had previously found that in Col1a1(Jrt/+) mice, a model of severe OI, treatment with an anti-scle...

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Detalles Bibliográficos
Autores principales: Marulanda, Juliana, Tauer, Josephine T., Boraschi-Diaz, Iris, Bardai, Ghalib, Rauch, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043013/
https://www.ncbi.nlm.nih.gov/pubmed/36973504
http://dx.doi.org/10.1038/s41598-023-32221-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043013/
https://www.ncbi.nlm.nih.gov/pubmed/36973504
http://dx.doi.org/10.1038/s41598-023-32221-3

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