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Effect of sclerostin inactivation in a mouse model of severe dominant osteogenesis imperfecta
Osteogenesis imperfecta (OI) is a rare bone disease that is associated with fractures and low bone mass. Sclerostin inhibition is being evaluated as a potential approach to increase bone mass in OI. We had previously found that in Col1a1(Jrt/+) mice, a model of severe OI, treatment with an anti-scle...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043013/ https://www.ncbi.nlm.nih.gov/pubmed/36973504 http://dx.doi.org/10.1038/s41598-023-32221-3 |