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Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis

Liver-resident natural killer cells, a unique lymphocyte subset in liver, develop locally and play multifaceted immunological roles. However, the mechanisms for the maintenance of liver-resident natural killer cell homeostasis remain unclear. Here we show that early-life antibiotic treatment blunt f...

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Detalles Bibliográficos
Autores principales: Tian, Panpan, Yang, Wenwen, Guo, Xiaowei, Wang, Tixiao, Tan, Siyu, Sun, Renhui, Xiao, Rong, Wang, Yuzhen, Jiao, Deyan, Xu, Yachen, Wei, Yanfei, Wu, Zhuanchang, Li, Chunyang, Gao, Lifen, Ma, Chunhong, Liang, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043027/
https://www.ncbi.nlm.nih.gov/pubmed/36973277
http://dx.doi.org/10.1038/s41467-023-37419-7