Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge

Despite numerous clinically available vaccines and therapeutics, aged patients remain at increased risk for COVID-19 morbidity. Furthermore, various patient populations, including the aged can have suboptimal responses to SARS-CoV-2 vaccine antigens. Here, we characterized vaccine-induced responses...

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Detalles Bibliográficos
Autores principales: Gary, Ebony N., Tursi, Nicholas J., Warner, Bryce M., Cuismano, Gina, Connors, Jennifer, Parzych, Elizabeth M., Griffin, Bryan D., Bell, Matthew R., Ali, Ali R., Frase, Drew, Hojecki, Casey E., Canziani, Gabriela A., Chaiken, Irwin, Kannan, Toshitha, Moffat, Estella, Embury-Hyatt, Carissa, Wooton, Sarah K., Kossenkov, Andrew, Patel, Ami, Kobasa, Darwyn, Kutzler, Michele A., Haddad, Elias K., Weiner, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043169/
https://www.ncbi.nlm.nih.gov/pubmed/36999023
http://dx.doi.org/10.3389/fimmu.2023.1138609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043169/
https://www.ncbi.nlm.nih.gov/pubmed/36999023
http://dx.doi.org/10.3389/fimmu.2023.1138609

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