Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway

Background: Idiopathic pulmonary fibrosis is a severe and deadly form of diffuse parenchymal lung disease and treatment options are few. Alveolar epithelial type 2 (AEC2) cell senescence is implicated in the pathogenies of IPF. A major bioactive compound from the traditional Chinese medicine Fructus...

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Detalles Bibliográficos
Autores principales: Xiong, Dian, Gao, Fei, Shao, Jingbo, Pan, Yueyun, Wang, Song, Wei, Dong, Ye, Shugao, Chen, Yuan, Chen, Rui, Yue, Bingqing, Li, Juan, Chen, Jingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043219/
https://www.ncbi.nlm.nih.gov/pubmed/36998607
http://dx.doi.org/10.3389/fphar.2023.1141800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043219/
https://www.ncbi.nlm.nih.gov/pubmed/36998607
http://dx.doi.org/10.3389/fphar.2023.1141800

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