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Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development

Biomarkers are quantifiable characteristics of biological processes. In Mycobacterium tuberculosis, common biomarkers used in clinical drug development are colony forming unit (CFU) and time-to-positivity (TTP) from sputum samples. This analysis aimed to develop a combined quantitative tuberculosis...

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Detalles Bibliográficos
Autores principales: Ayoun Alsoud, Rami, Svensson, Robin J., Svensson, Elin M., Gillespie, Stephen H., Boeree, Martin J., Diacon, Andreas H., Dawson, Rodney, Aarnoutse, Rob E., Simonsson, Ulrika S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043246/
https://www.ncbi.nlm.nih.gov/pubmed/36998606
http://dx.doi.org/10.3389/fphar.2023.1067295