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Structural and functional analysis of human pannexin 2 channel

The pannexin 2 channel (PANX2) participates in multiple physiological processes including skin homeostasis, neuronal development, and ischemia-induced brain injury. However, the molecular basis of PANX2 channel function remains largely unknown. Here, we present a cryo-electron microscopy structure o...

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Detalles Bibliográficos
Autores principales: He, Zhihui, Zhao, Yonghui, Rau, Michael J., Fitzpatrick, James A. J., Sah, Rajan, Hu, Hongzhen, Yuan, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043284/
https://www.ncbi.nlm.nih.gov/pubmed/36973289
http://dx.doi.org/10.1038/s41467-023-37413-z