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Novel 2-substituted-5-(4-chloro-2-phenoxy)phenyl-1,3,4-oxadiazole derivatives, ligands of GABAA/benzodiazepine receptor complex: Design, synthesis, radioligand binding assay, and pharmacological evaluation

Agonists of Benzodiazepine (BZD) receptor are exhaustively used in the control of muscle spasms, seizure, anxiety, and insomnia. BZDs have some unwanted effects; therefore, the development of new BZD receptor agonists with better efficacy and fewer unwanted effects is one of the subjects of interest...

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Detalles Bibliográficos
Autores principales: Rezaee, Elham, Ahmadi, Fatemeh, Shabaninia, Mahsa, Khoramjouy, Mona, Azizi Farsani, Zahra, Shahhosseini, Soraya, Tabatabai, Sayyed Abbas, Faizi, Mehrdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043390/
https://www.ncbi.nlm.nih.gov/pubmed/36998711
http://dx.doi.org/10.17179/excli2022-5639