First in man study: Bcl-Xl_42-CAF(®)09b vaccines in patients with locally advanced prostate cancer

BACKGROUND: The B-cell lymphoma-extra-large (Bcl-XL) protein plays an important role in cancer cells’ resistance to apoptosis. Pre-clinical studies have shown that vaccination with Bcl-XL-derived peptides can induce tumor-specific T cell responses that may lead to the elimination of cancer cells. Fu...

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Detalles Bibliográficos
Autores principales: Mørk, Sofie Kirial, Kongsted, Per, Westergaard, Marie Christine Wulff, Albieri, Benedetta, Granhøj, Joachim Stoltenborg, Donia, Marco, Martinenaite, Evelina, Holmström, Morten Orebo, Madsen, Kasper, Kverneland, Anders H., Kjeldsen, Julie Westerlin, Holmstroem, Rikke Boedker, Lorentzen, Cathrine Lund, Nørgaard, Nis, Andreasen, Lars Vibe, Wood, Grith Krøyer, Christensen, Dennis, Klausen, Michael Schantz, Hadrup, Sine Reker, thor Straten, Per, Andersen, Mads Hald, Svane, Inge Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043415/
https://www.ncbi.nlm.nih.gov/pubmed/36999039
http://dx.doi.org/10.3389/fimmu.2023.1122977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043415/
https://www.ncbi.nlm.nih.gov/pubmed/36999039
http://dx.doi.org/10.3389/fimmu.2023.1122977

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