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First in man study: Bcl-Xl_42-CAF(®)09b vaccines in patients with locally advanced prostate cancer
BACKGROUND: The B-cell lymphoma-extra-large (Bcl-XL) protein plays an important role in cancer cells’ resistance to apoptosis. Pre-clinical studies have shown that vaccination with Bcl-XL-derived peptides can induce tumor-specific T cell responses that may lead to the elimination of cancer cells. Fu...
Autores principales: | Mørk, Sofie Kirial, Kongsted, Per, Westergaard, Marie Christine Wulff, Albieri, Benedetta, Granhøj, Joachim Stoltenborg, Donia, Marco, Martinenaite, Evelina, Holmström, Morten Orebo, Madsen, Kasper, Kverneland, Anders H., Kjeldsen, Julie Westerlin, Holmstroem, Rikke Boedker, Lorentzen, Cathrine Lund, Nørgaard, Nis, Andreasen, Lars Vibe, Wood, Grith Krøyer, Christensen, Dennis, Klausen, Michael Schantz, Hadrup, Sine Reker, thor Straten, Per, Andersen, Mads Hald, Svane, Inge Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043415/ https://www.ncbi.nlm.nih.gov/pubmed/36999039 http://dx.doi.org/10.3389/fimmu.2023.1122977 |
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