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Anti-tumor effects of low-dose metronomic vinorelbine in combination with alpelisib in breast cancer cells

In metastatic breast cancer (MBC), PIK3CA mutations, activating the phosphatidylinositol 3-kinase (PI3K) signaling pathway seem to be associated with chemotherapy resistance and poor outcome. Inhibition of the PI3K signaling pathway may lead to sensitization and prevention of the development of resi...

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Detalles Bibliográficos
Autores principales: Krajnak, Slavomir, Trier, Jannis Patrik, Heinzmann, Pauline Friederike, Anic, Katharina, Heimes, Anne-Sophie, Loewe, Amelie, Schmidt, Marcus, Battista, Marco Johannes, Hasenburg, Annette, Brenner, Walburgis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043427/
https://www.ncbi.nlm.nih.gov/pubmed/36998707
http://dx.doi.org/10.17179/excli2022-5064