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Caspase 6/NR4A1/SOX9 signaling axis regulates hepatic inflammation and pyroptosis in ischemia-stressed fatty liver

The mechanism of nonalcoholic fatty liver susceptibility to ischemia/reperfusion (IR) injury has not been fully clarified. Caspase 6 is a critical regulator in innate immunity and host defense. We aimed to characterize the specific role of Caspase 6 in IR-induced inflammatory responses in fatty live...

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Detalles Bibliográficos
Autores principales: Sheng, Mingwei, Weng, Yiqi, Cao, Yingli, Zhang, Chen, Lin, Yuanbang, Yu, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043527/
https://www.ncbi.nlm.nih.gov/pubmed/36977670
http://dx.doi.org/10.1038/s41420-023-01396-z