Exploring the Limits of Cyanobactin Macrocyclase PatGmac: Cyclization of PawS-Derived Peptide Sunflower Trypsin Inhibitor-1 and Cyclotide Kalata B1

[Image: see text] The subtilisin-like macrocyclase PatGmac is produced by the marine cyanobacterium Prochloron didemni. This enzyme is involved in the last step of the biosynthesis of patellamides, a cyanobactin type of ribosomally expressed and post-translationally modified cyclic peptides. PatGmac...

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Detalles Bibliográficos
Autores principales: Muhammad, Taj, Houssen, Wael E, Thomas, Louise, Alexandru-Crivac, Cristina-Nicoleta, Gunasekera, Sunithi, Jaspars, Marcel, Göransson, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043927/
https://www.ncbi.nlm.nih.gov/pubmed/36917740
http://dx.doi.org/10.1021/acs.jnatprod.2c01158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043927/
https://www.ncbi.nlm.nih.gov/pubmed/36917740
http://dx.doi.org/10.1021/acs.jnatprod.2c01158

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