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Large and stable genome edits at the sorghum alpha kafirin locus result in changes in chromatin accessibility and globally increased expression of genes encoding lysine enrichment

INTRODUCTION: Sorghum is a resilient and widely cultivated grain crop used for feed and food. However, it’s grain is deficient in lysine, an essential amino acid. This is due to the primary seed storage proteins, the alpha-kafirins, lacking lysine. It has been observed that reductions in alpha-kafir...

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Detalles Bibliográficos
Autores principales: Hurst, J. Preston, Yobi, Abou, Li, Aixia, Sato, Shirley, Clemente, Thomas E., Angelovici, Ruthie, Holding, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10043997/
https://www.ncbi.nlm.nih.gov/pubmed/36998682
http://dx.doi.org/10.3389/fpls.2023.1116886