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Comparison of the efficacy and safety of methotrexate alone or in combination with leflunomide in the treatment of juvenile idiopathic arthritis: a double-blind, placebo-controlled, randomized trial

INTRODUCTION: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disorder in children. Although methotrexate (MTX) is the first line disease-modifying antirheumatic drug for JIA, many patients do not respond well or cannot tolerate MTX. The aim of this study was to compare the...

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Detalles Bibliográficos
Autores principales: Rezaieyazdi, Zahra, Ravanshad, Sahar, Khodashahi, Mandana, Bokaeian, Maliheh, Mehrad Majd, Hassan, Salari, Masoumeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044028/
https://www.ncbi.nlm.nih.gov/pubmed/36998586
http://dx.doi.org/10.5114/reum/161317