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The influence of single-point mutation D614G on the binding process between human angiotensin-converting enzyme 2 and the SARS-CoV-2 spike protein-an atomistic simulation study

SARS-CoV-2 has continuously evolved as changes in the genetic code occur during replication of the genome, with some of the mutations leading to higher transmission among human beings. The spike aspartic acid-614 to glycine (D614G) substitution in the spike represents a “more transmissible form of S...

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Detalles Bibliográficos
Autores principales: Shi, Chengcheng, Jiao, Yanqi, Yang, Chao, Sun, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044093/
https://www.ncbi.nlm.nih.gov/pubmed/36998522
http://dx.doi.org/10.1039/d3ra00198a