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Melanoma-associated repair-like Schwann cells suppress anti-tumor T-cells via 12/15-LOX/COX2-associated eicosanoid production

Peripheral glia, specifically the Schwann cells (SCs), have been implicated in the formation of the tumor microenvironment (TME) and in cancer progression. However, in vivo and ex vivo analyses of how cancers reprogram SC functions in different organs of tumor-bearing mice are lacking. We generated...

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Detalles Bibliográficos
Autores principales: Kruglov, Oleg, Vats, Kavita, Soman, Vishal, Tyurin, Vladimir A., Tyurina, Yulia Y., Wang, Jiefei, Williams, Li’an, Zhang, Jiying, Donahue Carey, Cara, Jaklitsch, Erik, Chandran, Uma R., Bayir, Hülya, Kagan, Valerian E., Bunimovich, Yuri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044150/
https://www.ncbi.nlm.nih.gov/pubmed/36998620
http://dx.doi.org/10.1080/2162402X.2023.2192098