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Cell-autonomous reduction of CYFIP2 is insufficient to induce Alzheimer's disease-like pathologies in the hippocampal CA1 pyramidal neurons of aged mice

Cytoplasmic FMR1-interacting protein 2 (CYFIP2) is an evolutionarily conserved multifunctional protein that regulates the neuronal actin cytoskeleton, mRNA translation and transport, and mitochondrial morphology and function. Supporting its critical roles in proper neuronal development and function,...

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Detalles Bibliográficos
Autores principales: Ma, Ruiying, Zhang, Yinhua, Li, Huiling, Kang, Hyae Rim, Kim, Yoonhee, Han, Kihoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044167/
https://www.ncbi.nlm.nih.gov/pubmed/36999135
http://dx.doi.org/10.1080/19768354.2023.2192263