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Monensin, an Antibiotic Isolated from Streptomyces Cinnamonensis, Regulates Human Neuroblastoma Cell Proliferation via the PI3K/AKT Signaling Pathway and Acts Synergistically with Rapamycin

Neuroblastoma is the most common extracranial childhood tumor and accounts for approximately 15% of pediatric cancer-related deaths. Further studies are needed to identify potential therapeutic targets for neuroblastoma. Monensin is an ionophore antibiotic obtained from Streptomyces cinnamonensis wi...

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Detalles Bibliográficos
Autores principales: Serter Kocoglu, Sema, Secme, Mücahit, Oy, Ceren, Korkusuz, Gözde, Elmas, Levent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044236/
https://www.ncbi.nlm.nih.gov/pubmed/36978413
http://dx.doi.org/10.3390/antibiotics12030546