Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation

BACKGROUND: Breast cancer is the most common tumor in women worldwide. Diabetes mellitus is a global chronic metabolic disease with increasing incidence. Diabetes mellitus has been reported to positively regulate the development of many tumors. However, the specific mechanism of hyperglycemic enviro...

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Detalles Bibliográficos
Autores principales: Cheng, Xiao, Jia, Xiupeng, Wang, Chunnian, Zhou, Shangyan, Chen, Jiayi, Chen, Lei, Chen, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044395/
https://www.ncbi.nlm.nih.gov/pubmed/36973739
http://dx.doi.org/10.1186/s12957-023-02990-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044395/
https://www.ncbi.nlm.nih.gov/pubmed/36973739
http://dx.doi.org/10.1186/s12957-023-02990-2

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