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Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations

Pathogenic Acanthamoeba produce keratitis and fatal granulomatous amoebic encephalitis. Treatment remains problematic and often ineffective, suggesting the need for the discovery of novel compounds. For the first time, here we evaluated the effects of the anticancer drugs Irosustat and STX140 alone,...

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Detalles Bibliográficos
Autores principales: Siddiqui, Ruqaiyyah, Rawas-Qalaji, Mutasem, El-Gamal, Mohammed I., Sajeev, Sreedevi, Jagal, Jayalakshmi, Zaraei, Seyed-Omar, Sbenati, Rawan M., Anbar, Hanan S., Dohle, Wolfgang, Potter, Barry V. L., Khan, Naveed Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044433/
https://www.ncbi.nlm.nih.gov/pubmed/36978428
http://dx.doi.org/10.3390/antibiotics12030561