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Non-Toxigenic Clostridioides difficile Strain E4 (NTCD-E4) Prevents Establishment of Primary C. difficile Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model

Clostridioides difficile infection (CDI) remains a significant healthcare burden. Non-toxigenic C. difficile (NTCD) strains have shown a benefit in preventing porcine enteritis and in human recurrent CDI. In this study, we evaluated the efficacy of metronidazole-resistant NTCD-E4 in preventing CDI f...

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Detalles Bibliográficos
Autores principales: Etifa, Perezimor, Rodríguez, César, Harmanus, Céline, Sanders, Ingrid M. J. G., Sidorov, Igor A., Mohammed, Olufunmilayo A., Savage, Emily, Timms, Andrew R., Freeman, Jane, Smits, Wiep Klaas, Wilcox, Mark H., Baines, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044524/
https://www.ncbi.nlm.nih.gov/pubmed/36978302
http://dx.doi.org/10.3390/antibiotics12030435