Epigenetics in Canine Mammary Tumors: Upregulation of miR-18a and miR-18b Oncogenes Is Associated with Decreased ERS1 Target mRNA Expression and ERα Immunoexpression in Highly Proliferating Carcinomas

SIMPLE SUMMARY: Canine mammary neoplasms commonly lose ERα expression along with an increase in stage and grade, negatively correlating with patient prognosis. The ESR1 gene encodes ERα and represents an important target mRNA for miR-18a and miR-18b, described as overexpressed oncogenes in canine ma...

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Detalles Bibliográficos
Autores principales: Abbate, Jessica Maria, Arfuso, Francesca, Riolo, Kristian, Capparucci, Fabiano, Brunetti, Barbara, Lanteri, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044548/
https://www.ncbi.nlm.nih.gov/pubmed/36978627
http://dx.doi.org/10.3390/ani13061086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044548/
https://www.ncbi.nlm.nih.gov/pubmed/36978627
http://dx.doi.org/10.3390/ani13061086

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