Knockout of Rlim Results in a Sex Ratio Shift toward Males but Superovulation Cannot Compensate for the Reduced Litter Size

SIMPLE SUMMARY: Maternal Rlim is required for imprinted X-chromosome inactivation (XCI), which is essential for normal development of female mouse embryos. In this study, we used a novel approach to inactivate the maternal Rlim allele in female embryos, resulting in a male sex-ratio shift in the off...

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Detalles Bibliográficos
Autores principales: Peng, Jingfeng, Hou, Yunfei, Wu, Shici, Li, Zicong, Wu, Zhenfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044649/
https://www.ncbi.nlm.nih.gov/pubmed/36978620
http://dx.doi.org/10.3390/ani13061079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044649/
https://www.ncbi.nlm.nih.gov/pubmed/36978620
http://dx.doi.org/10.3390/ani13061079

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