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Knockout of Rlim Results in a Sex Ratio Shift toward Males but Superovulation Cannot Compensate for the Reduced Litter Size
SIMPLE SUMMARY: Maternal Rlim is required for imprinted X-chromosome inactivation (XCI), which is essential for normal development of female mouse embryos. In this study, we used a novel approach to inactivate the maternal Rlim allele in female embryos, resulting in a male sex-ratio shift in the off...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044649/ https://www.ncbi.nlm.nih.gov/pubmed/36978620 http://dx.doi.org/10.3390/ani13061079 |