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Neuroprotection of NRF2 against Ferroptosis after Traumatic Brain Injury in Mice

Ferroptosis and iron-related redox imbalance aggravate traumatic brain injury (TBI) outcomes. NRF2 is the predominant transcription factor regulating oxidative stress and neuroinflammation in TBI, but its role in iron-induced post-TBI damage is unclear. We investigated ferroptotic neuronal damage in...

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Detalles Bibliográficos
Autores principales: Cheng, Hao, Wang, Pengfei, Wang, Ning, Dong, Wenwen, Chen, Ziyuan, Wu, Mingzhe, Wang, Ziwei, Yu, Ziqi, Guan, Dawei, Wang, Linlin, Zhao, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044792/
https://www.ncbi.nlm.nih.gov/pubmed/36978979
http://dx.doi.org/10.3390/antiox12030731