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Upregulation of Sarcolemmal Hemichannels and Inflammatory Transcripts with Neuromuscular Junction Instability during Lower Limb Unloading in Humans

SIMPLE SUMMARY: Skeletal muscles need to be continually active. Physical inactivity, reduced gravity, such as when humans are in space, or aging itself can cause neuromuscular frailty and weakness, causing major diseases. Comprehension of the molecular mechanisms that cause skeletal muscle atrophy c...

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Detalles Bibliográficos
Autores principales: Sirago, Giuseppe, Candia, Julián, Franchi, Martino V., Sarto, Fabio, Monti, Elena, Toniolo, Luana, Reggiani, Carlo, Giacomello, Emiliana, Zampieri, Sandra, Hartnell, Lisa M., De Vito, Giuseppe, Sandri, Marco, Ferrucci, Luigi, Narici, Marco V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044797/
https://www.ncbi.nlm.nih.gov/pubmed/36979123
http://dx.doi.org/10.3390/biology12030431