Cargando…

Upregulation of Sarcolemmal Hemichannels and Inflammatory Transcripts with Neuromuscular Junction Instability during Lower Limb Unloading in Humans

SIMPLE SUMMARY: Skeletal muscles need to be continually active. Physical inactivity, reduced gravity, such as when humans are in space, or aging itself can cause neuromuscular frailty and weakness, causing major diseases. Comprehension of the molecular mechanisms that cause skeletal muscle atrophy c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sirago, Giuseppe, Candia, Julián, Franchi, Martino V., Sarto, Fabio, Monti, Elena, Toniolo, Luana, Reggiani, Carlo, Giacomello, Emiliana, Zampieri, Sandra, Hartnell, Lisa M., De Vito, Giuseppe, Sandri, Marco, Ferrucci, Luigi, Narici, Marco V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044797/ https://www.ncbi.nlm.nih.gov/pubmed/36979123 http://dx.doi.org/10.3390/biology12030431

Ejemplares similares

Neuromuscular junction instability and altered intracellular calcium handling as early determinants of force loss during unloading in humans
por: Monti, Elena, et al.
Publicado: (2021)

Effects of short‐term unloading and active recovery on human motor unit properties, neuromuscular junction transmission and transcriptomic profile
por: Sarto, Fabio, et al.
Publicado: (2022)

Plasma proteome profiling of healthy subjects undergoing bed rest reveals unloading‐dependent changes linked to muscle atrophy
por: Murgia, Marta, et al.
Publicado: (2022)

Golgi Complex form and Function: A Potential Hub Role Also in Skeletal Muscle Pathologies?
por: Toniolo, Luana, et al.
Publicado: (2022)

The Contribution of Genetics to Muscle Disuse, Retraining, and Aging
por: Sirago, Giuseppe, et al.
Publicado: (2022)

Skeletal Muscle Mitochondrial and Perilipin Content in a Cohort of Obese Subjects Undergoing Moderate and High Intensity Training
por: Sirago, Giuseppe, et al.
Publicado: (2022)

Effects of a 2‐year exercise training on neuromuscular system health in older individuals with low muscle function
por: Monti, Elena, et al.
Publicado: (2023)

The Potential of Calorie Restriction and Calorie Restriction Mimetics in Delaying Aging: Focus on Experimental Models
por: Giacomello, Emiliana, et al.
Publicado: (2021)

Nutrition, Diet and Healthy Aging
por: Giacomello, Emiliana, et al.
Publicado: (2021)

Editorial: The fiber profile of skeletal muscles as a fingerprint of muscle quality
por: Giacomello, Emiliana, et al.
Publicado: (2022)

Age Dependent Modification of the Metabolic Profile of the Tibialis Anterior Muscle Fibers in C57BL/6J Mice
por: Giacomello, Emiliana, et al.
Publicado: (2020)

Resveratrol, a Multitasking Molecule That Improves Skeletal Muscle Health
por: Toniolo, Luana, et al.
Publicado: (2023)

Changes in Biceps Femoris Long Head Fascicle Length after 10-d Bed Rest Assessed with Different Ultrasound Methods
por: SARTO, FABIO, et al.
Publicado: (2021)

Physical active lifestyle promotes static and dynamic balance performance in young and older adults
por: Sarto, Fabio, et al.
Publicado: (2022)

Signatures of muscle disuse in spaceflight and bed rest revealed by single muscle fiber proteomics
por: Murgia, Marta, et al.
Publicado: (2022)

C‐terminal agrin fragment as a biomarker of muscle wasting and weakness: a narrative review
por: Monti, Elena, et al.
Publicado: (2023)

Costamere remodeling with muscle loading and unloading in healthy young men
por: Li, Ruowei, et al.
Publicado: (2013)

Implementing Ultrasound Imaging for the Assessment of Muscle and Tendon Properties in Elite Sports: Practical Aspects, Methodological Considerations and Future Directions
por: Sarto, Fabio, et al.
Publicado: (2021)

The Time-Course of Changes in Muscle Mass, Architecture and Power During 6 Weeks of Plyometric Training
por: Monti, Elena, et al.
Publicado: (2020)

Magnetic resonance imaging based muscle strain rate mapping during eccentric contraction to study effects of unloading induced by unilateral limb suspension
por: Sinha, Usha, et al.
Publicado: (2020)

Hemichannel-mediated release of lactate
por: Karagiannis, Anastassios, et al.
Publicado: (2015)

Abstracts of the 2023 Padua Days of Muscle and Mobility Medicine (2023Pdm3) to be held March 29 - April 1 at the Galileian Academy of Padua and at the Petrarca Hotel, Thermae of Euganean Hills, Padua, Italy
por: Zampieri, Sandra, et al.
Publicado: (2023)

Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations
por: Franchi, Martino V., et al.
Publicado: (2017)

Role of the Extracellular Matrix in Loss of Muscle Force With Age and Unloading Using Magnetic Resonance Imaging, Biochemical Analysis, and Computational Models
por: Sinha, Usha, et al.
Publicado: (2020)

SARCOLEMMAL INVAGINATIONS CONSTITUTING THE T SYSTEM IN FISH MUSCLE FIBERS
por: Franzini-armstrong, Clara, et al.
Publicado: (1964)

AMPK Complex Activation Promotes Sarcolemmal Repair in Dysferlinopathy
por: Ono, Hiroya, et al.
Publicado: (2020)

Mitochondrial Ca(2+)-Handling in Fast Skeletal Muscle Fibers from Wild Type and Calsequestrin-Null Mice
por: Scorzeto, Michele, et al.
Publicado: (2013)

Connexin hemichannels in the lens
por: Beyer, Eric C., et al.
Publicado: (2014)

Alterations of Extracellular Matrix Mechanical Properties Contribute to Age-Related Functional Impairment of Human Skeletal Muscles
por: Pavan, Piero, et al.
Publicado: (2020)

Editorial: Physiology and Clinical Potential of Eccentric Exercise
por: Franchi, Martino V., et al.
Publicado: (2017)

Eccentric Exercise and the Critically Ill Patient
por: Mitchell, W. Kyle, et al.
Publicado: (2017)

Bouncing Back! Counteracting Muscle Aging With Plyometric Muscle Loading
por: Franchi, Martino V., et al.
Publicado: (2019)

SARCOLEMMAL SCALLOPING AT SHORT SARCOMERE LENGTHS WITH INCIDENTAL OBSERVATIONS ON THE T TUBULES
por: Hagopian, Martin, et al.
Publicado: (1972)

Neural Activation During Submaximal Contractions Seems More Reflective of Neuromuscular Ageing than Maximal Voluntary Activation
por: Scaglioni, Gil, et al.
Publicado: (2016)

Fascicle length does increase in response to longitudinal resistance training and in a contraction-mode specific manner
por: Franchi, Martino V., et al.
Publicado: (2016)

Tendon Adaptations to Eccentric Exercise and the Implications for Older Adults
por: Quinlan, Jonathan I, et al.
Publicado: (2019)

Possible role of hemichannels in cancer
por: Schalper, Kurt A., et al.
Publicado: (2014)

Hemichannels; from the molecule to the function
por: Retamal, Mauricio A., et al.
Publicado: (2014)

Diseases associated with leaky hemichannels
por: Retamal, Mauricio A., et al.
Publicado: (2015)

Juvenile Neuromuscular Systems Show Amplified Disturbance to Muscle Unloading
por: Deschenes, Michael R., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_orefb73792p95kva4o3eocd8sb