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Defensin Interactions in Relation to Monoclonal and Disease-Related Proteinase 3 Antibodies Binding at the Catalytic Site

Proteinase 3 (PR3) is a neutrophil granulocyte enzyme and an autoantigen found in several forms of vasculitis. Due to the diagnostic and clinical importance of antibodies (Abs) to PR3, it is important to characterize the protein and the nature of its epitopes. Here, we have characterized PR3 monoclo...

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Detalles Bibliográficos
Autores principales: Zoega, Morten, Trier, Nicole Hartwig, Nejrup, Rikke Guldhammer, Chailyan, Anna, Friis, Tina, Højrup, Peter, Houen, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044823/
https://www.ncbi.nlm.nih.gov/pubmed/36975370
http://dx.doi.org/10.3390/antib12010023