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The CLDN5 gene at the blood-brain barrier in health and disease

The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain barrier (BBB), composed of brain microvascular endothelial cells and associated pericytes and end-feet of astrocytes, is...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yosuke, Greene, Chris, Munnich, Arnold, Campbell, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044825/
https://www.ncbi.nlm.nih.gov/pubmed/36978081
http://dx.doi.org/10.1186/s12987-023-00424-5