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The CLDN5 gene at the blood-brain barrier in health and disease
The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain barrier (BBB), composed of brain microvascular endothelial cells and associated pericytes and end-feet of astrocytes, is...
Autores principales: | Hashimoto, Yosuke, Greene, Chris, Munnich, Arnold, Campbell, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044825/ https://www.ncbi.nlm.nih.gov/pubmed/36978081 http://dx.doi.org/10.1186/s12987-023-00424-5 |
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