Epigenome-Wide Association Studies of the Fractional Exhaled Nitric Oxide and Bronchodilator Drug Response in Moderate-to-Severe Pediatric Asthma

Asthma is the most prevalent pediatric chronic disease. Bronchodilator drug response (BDR) and fractional exhaled nitric oxide (FeNO) are clinical biomarkers of asthma. Although DNA methylation (DNAm) contributes to asthma pathogenesis, the influence of DNAm on BDR and FeNO is scarcely investigated....

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Detalles Bibliográficos
Autores principales: Martin-Almeida, Mario, Perez-Garcia, Javier, Herrera-Luis, Esther, Rosa-Baez, Carlos, Gorenjak, Mario, Neerincx, Anne H., Sardón-Prado, Olaia, Toncheva, Antoaneta A., Harner, Susanne, Wolff, Christine, Brandstetter, Susanne, Valletta, Elisa, Abdel-Aziz, Mahmoud I., Hashimoto, Simone, Berce, Vojko, Corcuera-Elosegui, Paula, Korta-Murua, Javier, Buntrock-Döpke, Heike, Vijverberg, Susanne J. H., Verster, Joris C., Kerssemakers, Nikki, Hedman, Anna M, Almqvist, Catarina, Villar, Jesús, Kraneveld, Aletta D., Potočnik, Uroš, Kabesch, Michael, der Zee, Anke H. Maitland-van, Pino-Yanes, Maria, Consortium, on behalf of the SysPharmPediA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044864/
https://www.ncbi.nlm.nih.gov/pubmed/36979655
http://dx.doi.org/10.3390/biomedicines11030676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044864/
https://www.ncbi.nlm.nih.gov/pubmed/36979655
http://dx.doi.org/10.3390/biomedicines11030676

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