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Racial Differences in Androgen Receptor (AR) and AR Splice Variants (AR-SVs) Expression in Treatment-Naïve Androgen-Dependent Prostate Cancer

Androgen receptor splice variants (AR-SVs) contribute to the aggressive growth of castration-resistant prostate cancer (CRPC). AR-SVs, including AR-V7, are expressed in ~30% of CRPC, but minimally in treatment-naïve primary prostate cancer (PCa). Compared to Caucasian American (CA) men, African Amer...

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Detalles Bibliográficos
Autores principales: Khan, Farhan, Anelo, Obianuju Mercy, Sadiq, Qandeel, Effah, Wendy, Price, Gary, Johnson, Daniel L., Ponnusamy, Suriyan, Grimes, Brandy, Morrison, Michelle L., Fowke, Jay H., Hayes, D. Neil, Narayanan, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044992/
https://www.ncbi.nlm.nih.gov/pubmed/36979627
http://dx.doi.org/10.3390/biomedicines11030648