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The Role of Fucoxanthin as a Potent Nrf2 Activator via Akt/GSK-3β/Fyn Axis against Amyloid-β Peptide-Induced Oxidative Damage

Increasing evidence is suggesting that amyloid-β peptide (Aβ), a characteristic of Alzheimer’s disease (AD), induces oxidative stress and mitochondrial dysfunction, leading to neuronal death. This study aimed to demonstrate the antioxidant and anti-apoptotic effects of fucoxanthin, a major marine ca...

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Detalles Bibliográficos
Autores principales: Lee, Nayoung, Youn, Kumju, Yoon, Jeong-Hyun, Lee, Bokyung, Kim, Dong Hyun, Jun, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045033/
https://www.ncbi.nlm.nih.gov/pubmed/36978877
http://dx.doi.org/10.3390/antiox12030629