SARS-CoV-2 Main Protease Targets Host Selenoproteins and Glutathione Biosynthesis for Knockdown via Proteolysis, Potentially Disrupting the Thioredoxin and Glutaredoxin Redox Cycles

Associations between dietary selenium status and the clinical outcome of many viral infections, including SARS-CoV-2, are well established. Multiple independent studies have documented a significant inverse correlation between selenium status and the incidence and mortality of COVID-19. At the molec...

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Detalles Bibliográficos
Autores principales: Gallardo, Ignacio A., Todd, Daniel A., Lima, Stella T., Chekan, Jonathan R., Chiu, Norman H., Taylor, Ethan Will
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045059/
https://www.ncbi.nlm.nih.gov/pubmed/36978807
http://dx.doi.org/10.3390/antiox12030559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045059/
https://www.ncbi.nlm.nih.gov/pubmed/36978807
http://dx.doi.org/10.3390/antiox12030559

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