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SARS-CoV-2 Main Protease Targets Host Selenoproteins and Glutathione Biosynthesis for Knockdown via Proteolysis, Potentially Disrupting the Thioredoxin and Glutaredoxin Redox Cycles
Associations between dietary selenium status and the clinical outcome of many viral infections, including SARS-CoV-2, are well established. Multiple independent studies have documented a significant inverse correlation between selenium status and the incidence and mortality of COVID-19. At the molec...
Autores principales: | Gallardo, Ignacio A., Todd, Daniel A., Lima, Stella T., Chekan, Jonathan R., Chiu, Norman H., Taylor, Ethan Will |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045059/ https://www.ncbi.nlm.nih.gov/pubmed/36978807 http://dx.doi.org/10.3390/antiox12030559 |
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