Pre-treatment with IL-6 potentiates β-cell death induced by pro-inflammatory cytokines

BACKGROUND: Type I Diabetes mellitus (T1D) is characterized by a specific destruction of β-cells by the immune system. During this process pro-inflammatory cytokines are released in the pancreatic islets and contribute for β-cells demise. Cytokine-induced iNOS activation, via NF-κB, is implicated in...

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Detalles Bibliográficos
Autores principales: Oliveira, V. R., Paula, C. C., Taniguchi, S., Ortis, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045109/
https://www.ncbi.nlm.nih.gov/pubmed/36977992
http://dx.doi.org/10.1186/s12860-023-00476-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045109/
https://www.ncbi.nlm.nih.gov/pubmed/36977992
http://dx.doi.org/10.1186/s12860-023-00476-3

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