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Pre-treatment with IL-6 potentiates β-cell death induced by pro-inflammatory cytokines
BACKGROUND: Type I Diabetes mellitus (T1D) is characterized by a specific destruction of β-cells by the immune system. During this process pro-inflammatory cytokines are released in the pancreatic islets and contribute for β-cells demise. Cytokine-induced iNOS activation, via NF-κB, is implicated in...
Autores principales: | Oliveira, V. R., Paula, C. C., Taniguchi, S., Ortis, F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045109/ https://www.ncbi.nlm.nih.gov/pubmed/36977992 http://dx.doi.org/10.1186/s12860-023-00476-3 |
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