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Radiation-Induced Nephropathy in the Murine Model Is Ameliorated by Targeting Heparanase

Agents used to reduce adverse effects common in cancer treatment modalities do not typically possess tumor-suppressing properties. We report that heparanase, an extracellular matrix-degrading enzyme, is a promising candidate for preventing radiation nephropathy. Heparanase promotes tumor development...

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Detalles Bibliográficos
Autores principales: Abecassis, Alexia, Hermano, Esther, Sheva, Kim, Rubinstein, Ariel M., Elkin, Michael, Meirovitz, Amichay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045137/
https://www.ncbi.nlm.nih.gov/pubmed/36979689
http://dx.doi.org/10.3390/biomedicines11030710