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Over-Expressed GATA-1(S), the Short Isoform of the Hematopoietic Transcriptional Factor GATA-1, Inhibits Ferroptosis in K562 Myeloid Leukemia Cells by Preventing Lipid Peroxidation

Ferroptosis is a recently recognized form of regulated cell death involving lipid peroxidation. Glutathione peroxidase 4 (GPX4) plays a central role in the regulation of ferroptosis through the suppression of lipid peroxidation generation. Connections have been reported between ferroptosis, lipid me...

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Detalles Bibliográficos
Autores principales: Trombetti, Silvia, Iaccarino, Nunzia, Riccio, Patrizia, Sessa, Raffaele, Catapano, Rosa, Salvatore, Marcella, Luka, Stelina, de Nicola, Sergio, Izzo, Paola, Roperto, Sante, Maddalena, Pasqualino, Randazzo, Antonio, Grosso, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045147/
https://www.ncbi.nlm.nih.gov/pubmed/36978786
http://dx.doi.org/10.3390/antiox12030537