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Use of a pulmosphere model to evaluate drug antifibrotic responses in interstitial lung diseases

BACKGROUND: Interstitial lung diseases (ILD) encompass a heterogenous group of diffuse parenchymal lung disorders characterized by variable degrees of inflammation and fibrosis. Pretherapeutic clinical testing models for such diseases can serve as a platform to test and develop effective therapeutic...

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Detalles Bibliográficos
Autores principales: Dsouza, Kevin G., Surolia, Ranu, Kulkarni, Tejaswini, Li, Fu Jun, Singh, Pooja, Zeng, Huaxiu, Stephens, Crystal, Kumar, Abhishek, Wang, Zheng, Antony, Veena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045174/
https://www.ncbi.nlm.nih.gov/pubmed/36978076
http://dx.doi.org/10.1186/s12931-023-02404-7