The NGF R100W Mutation, Associated with Hereditary Sensory Autonomic Neuropathy Type V, Specifically Affects the Binding Energetic Landscapes of NGF and of Its Precursor proNGF and p75NTR

SIMPLE SUMMARY: A point mutation in the Nerve Growth factor gene (leading to the amino acid substitution R100W), causing Hereditary Sensory and Autonomic Neuropathy type V, a condition that primarily affects the sensory nerve cells, whose principal function is to transmit information about sensation...

Descripción completa

Detalles Bibliográficos
Autores principales: Covaceuszach, Sonia, Lamba, Doriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045213/
https://www.ncbi.nlm.nih.gov/pubmed/36979056
http://dx.doi.org/10.3390/biology12030364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045213/
https://www.ncbi.nlm.nih.gov/pubmed/36979056
http://dx.doi.org/10.3390/biology12030364

Ejemplares similares