A Preclinical Model for Parkinson’s Disease Based on Transcriptional Gene Activation via KEAP1/NRF2 to Develop New Antioxidant Therapies

Investigations of the effect of antioxidants on idiopathic Parkinson’s disease have been unsuccessful because the preclinical models used to propose these clinical studies do not accurately represent the neurodegenerative process of the disease. Treatment with certain exogenous neurotoxins induces m...

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Detalles Bibliográficos
Autores principales: Segura-Aguilar, Juan, Mannervik, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045214/
https://www.ncbi.nlm.nih.gov/pubmed/36978921
http://dx.doi.org/10.3390/antiox12030673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045214/
https://www.ncbi.nlm.nih.gov/pubmed/36978921
http://dx.doi.org/10.3390/antiox12030673

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