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Mitochondria Need Their Sleep: Redox, Bioenergetics, and Temperature Regulation of Circadian Rhythms and the Role of Cysteine-Mediated Redox Signaling, Uncoupling Proteins, and Substrate Cycles

HIGHLIGHTS: What are the main findings? Hypothesis: Redox, bioenergetic and temperature regulation is critical in maintaining cellular circadian rhythms; wakefulness is mainly “nucleorestorative” and sleep is mainly “mitorestorative”. Wakefulness: High metabolic rate induces oxidative stress and red...

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Detalles Bibliográficos
Autores principales: Richardson, Richard B., Mailloux, Ryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045244/
https://www.ncbi.nlm.nih.gov/pubmed/36978924
http://dx.doi.org/10.3390/antiox12030674