Cholesterol suppresses human iTreg differentiation and nTreg function through mitochondria-related mechanisms

BACKGROUND: Both the crystalline and soluble forms of cholesterol increase macrophage secretion of interleukin 1β (IL-1β), aggravating the inflammatory response in atherosclerosis (AS). However, the link between cholesterol and regulatory T cells (Tregs) remains unclear. This study aimed to investig...

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Detalles Bibliográficos
Autores principales: Zhang, Huanzhi, Xia, Ni, Tang, Tingting, Nie, Shaofang, Zha, Lingfeng, Zhang, Min, Lv, Bingjie, Lu, Yuzhi, Jiao, Jiao, Li, Jingyong, Cheng, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045251/
https://www.ncbi.nlm.nih.gov/pubmed/36973679
http://dx.doi.org/10.1186/s12967-023-03896-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045251/
https://www.ncbi.nlm.nih.gov/pubmed/36973679
http://dx.doi.org/10.1186/s12967-023-03896-z

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