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Cholesterol suppresses human iTreg differentiation and nTreg function through mitochondria-related mechanisms

BACKGROUND: Both the crystalline and soluble forms of cholesterol increase macrophage secretion of interleukin 1β (IL-1β), aggravating the inflammatory response in atherosclerosis (AS). However, the link between cholesterol and regulatory T cells (Tregs) remains unclear. This study aimed to investig...

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Detalles Bibliográficos
Autores principales:	Zhang, Huanzhi, Xia, Ni, Tang, Tingting, Nie, Shaofang, Zha, Lingfeng, Zhang, Min, Lv, Bingjie, Lu, Yuzhi, Jiao, Jiao, Li, Jingyong, Cheng, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045251/ https://www.ncbi.nlm.nih.gov/pubmed/36973679 http://dx.doi.org/10.1186/s12967-023-03896-z

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