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Overcoming EGFR Resistance in Metastatic Colorectal Cancer Using Vitamin C: A Review

Targeted monoclonal antibody therapy against Epidermal Growth Factor Receptor (EGFR) is a leading treatment modality against metastatic colorectal cancer (mCRC). However, with the emergence of KRAS and BRAF mutations, resistance was inevitable. Cells harboring these mutations overexpress Glucose Tra...

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Detalles Bibliográficos
Autores principales: Machmouchi, Ahmad, Chehade, Laudy, Temraz, Sally, Shamseddine, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045351/
https://www.ncbi.nlm.nih.gov/pubmed/36979659
http://dx.doi.org/10.3390/biomedicines11030678