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Overcoming EGFR Resistance in Metastatic Colorectal Cancer Using Vitamin C: A Review
Targeted monoclonal antibody therapy against Epidermal Growth Factor Receptor (EGFR) is a leading treatment modality against metastatic colorectal cancer (mCRC). However, with the emergence of KRAS and BRAF mutations, resistance was inevitable. Cells harboring these mutations overexpress Glucose Tra...
Autores principales: | Machmouchi, Ahmad, Chehade, Laudy, Temraz, Sally, Shamseddine, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045351/ https://www.ncbi.nlm.nih.gov/pubmed/36979659 http://dx.doi.org/10.3390/biomedicines11030678 |
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