Cargando…
Protective Potential of β-Hydroxybutyrate against Glucose-Deprivation-Induced Neurotoxicity Involving the Modulation of Autophagic Flux and the Monomeric Aβ Level in Neuro-2a Cells
Hypoglycemia has been known as a potential contributory factor to neurodegenerative diseases, such as Alzheimer’s disease. There may be shared pathogenic mechanisms underlying both conditions, and the ketone body, β-hydroxybutyrate (BHB), as an alternative substrate for glucose may exert neuroprotec...
Autores principales: | Chiang, Yi-Fen, Nguyen, Ngan Thi Kim, Hsia, Shih-Min, Chen, Hsin-Yuan, Lin, Shyh-Hsiang, Lin, Ching-I |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045359/ https://www.ncbi.nlm.nih.gov/pubmed/36979677 http://dx.doi.org/10.3390/biomedicines11030698 |
Ejemplares similares
-
Impairment of Autophagic Flux Promotes Glucose Reperfusion-Induced Neuro2A Cell Death after Glucose Deprivation
por: Jang, Bong Geom, et al.
Publicado: (2013) -
Caloric Restriction Alleviates CFA-Induced Inflammatory Pain via Elevating β-Hydroxybutyric Acid Expression and Restoring Autophagic Flux in the Spinal Cord
por: Liu, Chang, et al.
Publicado: (2022) -
ox-LDL induces autophagy-mediated apoptosis by suppressing secretagogin-regulated autophagic flux in pancreatic β-cells: SCGN regulates autophagic flux in β-cells
por: Lv, Ying, et al.
Publicado: (2022) -
β-hydroxybutyrate does not alter the effects of glucose deprivation on breast cancer cells
por: Maldonado, Rylee, et al.
Publicado: (2021) -
Acylated Ghrelin is Protective Against 6-OHDA-induced Neurotoxicity by Regulating Autophagic Flux
por: He, Xin, et al.
Publicado: (2021)